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Immune Deficiency Foundation Guide to Immunoglobulin Replacement Therapy for People Living with Primary Immunodeficiency Diseases

This guide was developed for patients and caregivers to help increase understanding of immunoglobulin (Ig) replacement therapy. An increased understanding puts patients and caregivers in a better position to make informed decisions regarding care. Education about the therapy can also build confidence and create a level of understanding that can reduce a patient’s anxiety about a treatment that can be frightening.


“I have a primary immunodeficiency disease. It’s long and hard to pronounce.”

Calleigh of Ridley Park, PA is a bright 8-year-old girl with a positive attitude who loves dancing and cats. She is also living with hypogammaglobulinemia, a type of primary immunodeficiency disease (PI). As she grew, so did her number of illnesses—despite the previous hope that her disease diagnosed at infancy was transient (she would grow out of it).

Monitoring ACA Patient Protections

Last week, the Department of Justice announced that it will not defend several critical patient protections in the Affordable Care Act (ACA), including the protection against denial of coverage for individuals with pre-existing conditions, in a lawsuit in Texas federal court. The suit is led by 20 states challenging the ACA’s validity after the repeal of the individual mandate last year. Sixteen states have filed a brief defending the law, including protections for people with pre-existing conditions.


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